|
|
L-alanine + holo-[SfmA_non-ribosomal_peptide_synthase] + ATP <=> L-alanyl-[SfmA_non-ribosomal_peptide_synthase] + AMP + diphosphate
|
6.2.1
|
–
|
| |
MetaCyc:
RXN-16724
|
|
|
|
presaframycin <=> saframycin_A
|
not assigned
|
–
|
| |
MetaCyc:
RXN-16716
|
|
|
|
S-adenosyl-L-methionine + 3-hydroxy-5-methyl-L-tyrosine <=> 4O,5-dimethyl,3-hydroxy_L-tyrosine + S-adenosyl-L-homocysteine + H+
|
2.1.1.M6
|
–
|
| |
MetaCyc:
RXN-16722
|
|
|
|
S-adenosyl-L-methionine + L-tyrosine <=> S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine + H+
|
2.1.1.304
L-tyrosine C3-methyltransferase
|
–
|
| |
BRENDA:
BR50860
KEGG:
R10964
MetaCyc:
RXN-15305
|
|
|
|
fatty_acid + holo-[SfmA_non-ribosomal_peptide_synthase] + ATP <=> acyl-[SfmA_non-ribosomal_peptide_synthase] + AMP + diphosphate
|
6.2.1
|
–
|
| |
MetaCyc:
RXN-16723
|
|
|
|
glycine + holo-[SfmB_glycyl-carrier_protein] + ATP <=> glycyl-[SfmB_glycyl-carrier-protein] + AMP + diphosphate
|
6.2.1.ad
|
–
|
| |
MetaCyc:
RXN-16726
|
|
|
|
acyl-L-alanyl-glycyl-[SfmB_peptidyl-carrier-protein] + 3O,4-dimethyl,5-hydroxy_L-tyrosyl-[SfmC_L-tyrosyl-carrier-protein] + NADPH <=> holo-[SfmB_glycyl-carrier_protein] + holo-[SfmC_tyrosyl-carrier-protein] + presaframycin + H2O + NADP+
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-16715
|
|
|
|
3-methyl-L-tyrosine + H2O2 <=> 3-hydroxy-5-methyl-L-tyrosine + H2O
|
1.11.1.7
peroxidase
1.11.2.5
3-methyl-L-tyrosine peroxygenase
|
–
–
|
| |
BRENDA:
BR50840
KEGG:
R10721
MetaCyc:
RXN-15302
|
|
|
|
acyl-[SfmA_non-ribosomal_peptide_synthase] + L-alanyl-[SfmA_non-ribosomal_peptide_synthase] + glycyl-[SfmB_glycyl-carrier-protein] <=> acyl-L-alanyl-glycyl-[SfmB_peptidyl-carrier-protein] + holo-[SfmA_non-ribosomal_peptide_synthase] + H+
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-16713
|
|
|
|
holo-[SfmC_tyrosyl-carrier-protein] + 4O,5-dimethyl,3-hydroxy_L-tyrosine + ATP <=> 3O,4-dimethyl,5-hydroxy_L-tyrosyl-[SfmC_L-tyrosyl-carrier-protein] + AMP + diphosphate
|
6.2.1
|
–
|
| |
MetaCyc:
RXN-16714
|
|
